In the conditions of low Signal-to-Noise Ratio ( SNR) of seismic data and a small quality of log information， the consequences of seismic interpretation through the impedance inversion of seismic data could be more precise． Constrained sparse spike inversion ( CSSI) has advantage in oil and gas reservoir predication because it does not rely on the original model． By analyzing the specific algorithm of CSSI，the accuracy of inversion is controlled． Oriente Basin in South America has the low amplitude in geological structure and complex lithologic trap． The well predication is obtained by the application of CSSI．