Based on the study of the cold phase of the Pacific Decade Oscillation, pandemic influenza is related to climate. The relation of low temperature, Pacific Decade Oscillation, strongest earthquake, Influenza, hurricane and El Nino is researched in this study. In the cold period of Pacific Decade Oscillation, the strongest earthquake, hurricane with La Nina, Pandemic Influenza with El Nino will occur stronger and stronger. From 1950 to 1976, the strongest dust-storm is connected with Pandemic Influenza one by one. So, dust-storm is one of factors to sp read pandemic influenza viruses.