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In order to depict lithologic distribution of Dalianhe Formation in Tangyuan Fault Depression subtly, lithologic prediction of log-constrained seismic, plentiful logging-seismic and drilling data have been used to fit out the functional relation of velocity-lithology. L ithologic prediction has been done after high-precision sequence stratigraphy constraint, and the coincidence rate of prediction result is up to 86%, which reveales the rule of lithologic spatial distribution is the high value area of sedimentary thickness and the thickness center of sand body distribute mainly in basin controlling faults side, and distribute mainly in the eastern dep ression zone near the basin boundary fault in the area.